Randomised comparison between a loading and incremental dose model for ritodrine administration in preterm labour

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Randomised comparison between a loading and incremental dose model for ritodrine administration in preterm labour.

OBJECTIVE To compare a new loading dose regimen for intravenous ritodrine administration in preterm labour with the conventional dose regimen. DESIGN Multicentre randomised trial using numbered opaque sealed envelopes. SETTING Five teaching hospitals in the Netherlands. PARTICIPANTS Women (n = 203) in preterm labour at less than 34 weeks of gestation. INTERVENTIONS Women received either...

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Tocolysis with Ritodrine: a Comparative Study in Preterm Labour

Objective: Preterm delivery is an important cause of perinatal morbidity and mortality. This study was conducted with an objective to assess the effect of ritodrine on perinatal mortality as compared to isoxsuprine and the effect of ritodrine on maternal morbidity and neonatal morbidity in comparison to isoxsuprine with the extent to which delivery was delayed. Design: A randomized study with 2...

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Ritodrine in the treatment of preterm labour: a meta-analysis.

BACKGROUND & OBJECTIVES Results on the effect of ritodrine in the treatment of preterm labour are different all over the world. Therefore, a concrete conclusion cannot be drawn from a single randomized control trial (RCT). In this study, we selected a large number of RCTs worldwide on the treatment of preterm labour comparing ritodrine and placebo or magnesium sulfate and by applying meta-analy...

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Effectiveness and safety of ritodrine hydrochloride for the treatment of preterm labour: a systematic review.

PURPOSE To analyse the available data on the effectiveness and safety of ritodrine hydrochloride in delaying delivery and in decreasing the incidence of preterm birth. METHODS Systematic review of randomised controlled trials (RCTs) that compared the effectiveness and safety of ritodrine hydrochloride with a placebo or with no treatment. Main outcome measures were relative risks (RRs) for per...

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A Prospective Randomized Study Comparing Nifedipine versus Ritodrine for the Suppression of Preterm Labour

Nifedipine is a dihydropyridine and a calcium channel blocker during the second phase of the action potential of uterine smooth muscle cells, and ritodrine is a ß-sympathomimetic. Objective of Study: To compare the efficacy and side-effects of oral nifedipine to ritodrine in the inhibition of preterm labour. Methodology: Sixty parturients admitted to the Maternity Hospital with preterm labour w...

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ژورنال

عنوان ژورنال: BJOG: An International Journal of Obstetrics and Gynaecology

سال: 1996

ISSN: 1470-0328,1471-0528

DOI: 10.1111/j.1471-0528.1996.tb09840.x